Sphingolipid Gel/Fluid Phase Transition Measurement by Integrated Resonance Probe Light - Archive ouverte HAL Accéder directement au contenu
Article Dans Une Revue Sensors & Transducers Journal Année : 2018

Sphingolipid Gel/Fluid Phase Transition Measurement by Integrated Resonance Probe Light

(1) , (1) , (1) , (2) , (1) , (1) , (3) , (1) , (4) , (1) , (1)
1
2
3
4
Lucas Garnier
V. Vié
Alain Moréac
Denis Morineau
Aziz Ghoufi
Etienne Gaviot
  • Fonction : Auteur
  • PersonId : 833839
  • IdRef : 070362556
Bruno Bêche

Résumé

The paper describes nanophotonic sensors realized by way of inexpensive organic processes. As hybrid silica/polymer resonators, they are suited to detect biological molecules in gel/fluid phase transition at infinitesimal concentrations (sphingomyelin lipids). Such a family of photonic structures is made of specific amplified deep UV210 photoresist-polymer waveguides coupled by a sub-wavelength gap with various racetrack micro-resonators. Thus, temperature dependent wavelength shifts characterizing the optical resonances of the device have been evaluated, highlighting a low thermal feature of the sensor, which is advantageous for this specific application. With an adapted vesicle lipid deposition process, specific in biology, together with an apt experimental thermo-photonic protocol, the dynamic evolution of the sphingomyelin lipid phase transition has been followed and assessed. The ability to detect their gel/fluid transition phase and melting temperature has been demonstrated with a mass product factor value 10^7 lower than that of classical methods as differential scanning calorimetry. The global equilibrium regimes of the coupling effect of resonances and the scattered part of the light are clearly highlighted as markedly modified by the dynamic of the sphingomyelin during its own phase transition.
Fichier principal
Vignette du fichier
SensorsTransducers_2018.pdf (758.85 Ko) Télécharger le fichier
Origine : Fichiers éditeurs autorisés sur une archive ouverte
Loading...

Dates et versions

hal-01888242 , version 1 (11-10-2018)

Identifiants

  • HAL Id : hal-01888242 , version 1

Citer

Qingyue Li, Lucas Garnier, V. Vié, Hervé Lhermite, Alain Moréac, et al.. Sphingolipid Gel/Fluid Phase Transition Measurement by Integrated Resonance Probe Light. Sensors & Transducers Journal, 2018, 225, pp.41 - 48. ⟨hal-01888242⟩
486 Consultations
170 Téléchargements

Partager

Gmail Facebook Twitter LinkedIn More