BYKdb: the Bacterial protein tYrosine Kinase database. - ECOFECT - Dynamiques éco-évolutives des maladies infectieuses
Article Dans Une Revue Nucleic Acids Research Année : 2012

BYKdb: the Bacterial protein tYrosine Kinase database.

Résumé

Bacterial tyrosine-kinases share no resemblance with their eukaryotic counterparts and they have been unified in a new protein family named BY-kinases. These enzymes have been shown to control several biological functions in the bacterial cells. In recent years biochemical studies, sequence analyses and structure resolutions allowed the deciphering of a common signature. However, BY-kinase sequence annotations in primary databases remain incomplete. This prompted us to develop a specialized database of computer-annotated BY-kinase sequences: the Bacterial protein tyrosine-kinase database (BYKdb). BY-kinase sequences are first identified, thanks to a workflow developed in a previous work. A second workflow annotates the UniProtKB entries in order to provide the BYKdb entries. The database can be accessed through a web interface that allows static and dynamic queries and offers integrated sequence analysis tools. BYKdb can be found at http://bykdb.ibcp.fr.

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hal-00965572 , version 1 (28-05-2020)

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Fanny Jadeau, Christophe Grangeasse, Lei Shi, Ivan Mijakovic, Gilbert Deléage, et al.. BYKdb: the Bacterial protein tYrosine Kinase database.. Nucleic Acids Research, 2012, 40 (Database issue), pp.D321-4. ⟨10.1093/nar/gkr915⟩. ⟨hal-00965572⟩
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